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Viral Diseases

Malignant Catarrhal Fever (MCF)


What is Malignant Catarrhal Fever (MCF)?
Malignant catarrhal fever (MCF) is a sporadic, occasionally epizootic, infectious disease of cattle, buffalo, and many species of wild ruminants caused by a herpesvirus. There are two forms of the disease. The form typically found outside of zoos in North America is associated with sheep. It affects cattle, bison, and deer species.

The virus affects the animals by attacking the lymph nodes and the walls of the blood vessels throughout the entire body, therefore many organs are affected and the appearance of the disease can be quite variable.

Transmission of MCF:
Transmission is thought to occur by ingestion, possibly by parturition fluid contamination of the pasture and/or feed.  The virus is transmitted from sheep or goats to deer.  There appears to be little or no transmission from deer to deer. Therefore the deer is the dead end host of MCF.

Stress is probably the major cause initiating the disease. The incidence of the disease rises during winter in herds that have no protection from the cold.

Symptoms of MCF:  
Typically the affected animal is lethargic, has a fever, cloudy eyes, diarrhea, sores in its mouth, enlarged lymph nodes and discharge from the eyes, mouth, and nose. The most common manifestation of Malignant Catarrhal Fever in deer is a rapid onset of bloody diarrhea, dark stained urine, depression, fever, and death within 48 hours.

Animals that live longer develop the chronic head-and-eye form that is typical of cattle. There is conjunctivitis, excessive salivation and eventually both eyes become cloudy. These animals live for a few days to a few weeks.

Where is MCF found?
Worldwide

Treatment of MCF:
There is no treatment available nor any viable control options.

Significance of MCF:
Outbreaks of MCF in North American cervids are uncommon and are almost always seen in captive deer. In addition to native deer, game farming animals such as antelope, bison and other deer are susceptible to the disease.  It is normally an irreversible, fatal disease.  MCF does not occur in humans.

 

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